Search results for " Biological computing"

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Boolean computation in plants using post-translational genetic control and a visual output signal

2018

[EN] Due to autotrophic growing capacity and extremely rich secondary metabolism, plants should be preferred targets of synthetic biology. However, developments in plants usually run below those in other taxonomic groups. In this work we engineered genetic circuits capable of logic YES, OR and AND Boolean computation in plant tissues with a visual output signal. The circuits, which are deployed by means of Agrobacterium tumefaciens, perform with the conditional activity of the MYB transcription factor Roseal from Antirrhinum majus inducing the accumulation of anthocyanins, plant endogenous pigments that are directly visible to the naked eye or accurately quantifiable by spectrophotometric a…

0106 biological sciences0301 basic medicineProteasesmedicine.medical_treatmentRecombinant Fusion ProteinsPotyvirusBiomedical EngineeringAgrobacterium01 natural sciencesBiochemistry Genetics and Molecular Biology (miscellaneous)Anthocyanins03 medical and health sciencesViral ProteinsAntirrhinum majusAnthocyanins Biological computingmedicineAntirrhinumMYBSecondary metabolismTranscription factorSynthetic biologyPlant ProteinsProteasebiologyfungiPotyvirusfood and beveragesGeneral MedicineAgrobacterium tumefaciensbiology.organism_classificationPlants Genetically ModifiedCell biologyGENETICA030104 developmental biologySpectrophotometryGenetic circuitsPotyvirus proteaseSynthetic BiologyProtein Processing Post-Translational010606 plant biology & botanyPeptide HydrolasesPlasmidsTranscription Factors
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